Bundesliga side, Schalke 04 will take on Premier League champions, Manchester City while struggling Manchester United have been matched against French champions PSG.
Champions League round of 16 draws:
In what is arguably the fixture of the round, Premier League leaders Liverpool will square up against German champions, Bayern Munich, Tottenham Hotspur faces a stern test in Borussia Dortmund while defending champions, Real Madrid have been drawn against Dutch giant, Ajax.
Italian side Roma will go head to head against Porto for a place in the quarterfinals while Spanish champions, Barcelona will face Lyon.
The first legs will hold on the 12-13 and 19-20 February with the return legs on 5-6 and 12-13 March 2019.